In short, yes. Though we will not have devastating results from not using it like the next generation cummins, it does help the lift pump and all parts of the fuel system. I noticed a ticking in my lift pump one day, dumped in some 2-stroke and it fixed it right up. Another thing I noticed was it does not smoke as much in the morning with the 2-stroke. Having the timing up, the beast hates the cold and smokes like a freight train until the EGT's are over 400, but the other day, I started it and couple minutes later went back over and said uhhh, wheres the smoke! All I saw was a blue haze instead of a white cloud. I am not exactly sure how 2-stroke can have such an impact on smoke with a cold engine but the results were obvious. I also believe it helps with MPG, the added power is enough to keep you off the pedal just a little bit more keeping you over 20 as long as you are under 75mph.