When rolling up my driver's side window, it'll start to chatter about half way up, or right when that leading corner hits the weatherstripping.  Has anyone else experienced that?  Do I get some silicone lubricant in there? Or replace the weatherstrip?

Mine screeches some times. Figured it was the fuzzy worn off of some wearher sripping at the bottom. LMC Truck sells it.

Try a little powdered graphite